The Future Value Creation Research Center, GSI-NU will hold the visiting scientist’s lecture on November 6.

The Future Value Creation Research Center, GSI-NU will hold the visiting scientist’s lecture on November 6.
Research Presentation will be held on November 6th.
1.Date:November 6th, 2018 15:00-16:00
2.Place:Future Value Creation Research Center, Room424, Bldg. B, School of Science
3.Speaker:Prof. Andrzej Kloczkowski
4.Title:Prediction and Modeling of Protein Structure, Dynamics and Stability
Recent progress in modeling of structure, dynamics and stability of proteins and other biomacromolecules will be reviewed. Prediction of protein tertiary structure from amino acid sequence will be discussed in detail. Recent advancements in structure prediction such as development of better potentials and force-fields (including multibody potentials), and improved modeling of free energies by taking into account the vibrational entropy will be presented. Different modeling methods of protein dynamics such as Molecular Dynamics simulations, Monte Carlo-based methods, normal mode analysis of protein fluctuational dynamics and elastic network models will be compared. I’ll discuss also various coarse grained methods of modeling protein structure and dynamics, prediction of deleterious mutations and modeling of the formation of protein and peptide aggregates.
Andrzej Kloczkowski obtained M.Sc. in Chemistry from the University of Warsaw, Poland in 1974, and Ph.D. in Physical Chemistry from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw in 1980. He obtained postdoctoral training at Stanford University, and worked in the past at the University of Cincinnati, National Cancer Institute, NIH in Bethesda, MD, and Iowa State University. Since 2010 he is Principal Investigator in the Battelle Center for Mathematical Medicine in the Research Institute of the Nationwide Children’s Hospital in Columbus, Ohio, and Professor in the Department of Pediatrics of The Ohio State University. He published 180 peer reviewed papers, and a co-edited a book Prediction of Protein Secondary Structure (Humana Press, New York, 2017). His research has been funded by the National Science Foundation and the National Institutes of Health. His research interests are Computational Biology and Computational Medicine.